The pivotal twin histidines and aromatic triad of theEscherichia coliammonium channel AmtB can be replaced
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چکیده
منابع مشابه
The pivotal twin histidines and aromatic triad of the Escherichia coli ammonium channel AmtB can be replaced.
In Escherichia coli, each subunit of the trimeric channel protein AmtB carries a hydrophobic pore for transport of NH(4)(+) across the cytoplasmic membrane. Positioned along this substrate conduction pathway are two conserved elements--a pair of hydrogen-bonded histidines (H168/H318) located within the pore itself and a set of aromatic residues (F107/W148/F215) at its periplasmic entrance--thou...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2011
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1108451108